Kanamycin sulfate from Streptomyces kanamycetikus, MP Biomedicals™

Kanamycin sulfate from Streptomyces kanamycetikus USP Grade, White Powder

Catalog Number	Quantity
MPB0219985305	5 g

Catalog number MPB0219985305

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Specifications

Physical FormPowder

CAS25389-94-0

pH6.5 to 8.5 (1% solution)

Melting Point>250°C

Storage Note 1Store at Room Temperature (15-30°C).

It is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus.
It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium.
Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene.
Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma.
It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding.
Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and partial cross-resistance has been reported between kanamycin and streptomycin. Aminoglycosidemodifying enzymes (acetyltransferase, phosphotransferase, nucleotidyltransferase) alter the antibiotic, preventing its interaction with ribosomes.