Cefotaxime Sodium Salt, MP Biomedicals™

Inhibits bacterial cell wall synthesis. Cefotaxime Sodium Salt, MP Biomedicals is a cephalosporin antibiotic that is active against both gram-negative and gram-positive bacteria. It is used for infections of the respiratory tract, skin, bones, joints, uro

Catalog Number	Quantity
MPB0215494791	1 g

Catalog number MPB0215494791

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Specifications

Physical FormPowder

CAS64485-93-4

Recommended StorageStore at 4°C, protect from light.

Quantity1 g

Molecular FormulaC16H16N5NaO7S2

Cefotaxime binds to penicillin-binding proteins (PBPs), which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes. Cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes. Cefotaxime is used to treat a variety of bacterial infections:

Good coverage against most Gram-negative bacteria, with the notable exception of Pseudomonas
Effective against most Gram-positive cocci, except for Enterococcus
Active against penicillin-resistant strains of Streptococcus pneumoniae
Modest activity against the anaerobic Bacteroides fragilis
In meningitis, cefotaxime crosses the blood–brain barrier better than cefuroxime