ProPac™ WCX-10 HPLC Columns
ProPac™ WCX-10 HPLC Columns
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Thermo Scientific

ProPac™ WCX-10 HPLC Columns

Separate proteins and their variants using these weak cation-exchange columns with exceptionally high resolution.

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Catalog NumberLength (Metric)Diameter (Metric)Column Format
FISDX054993250 mm4 mmAnalytical Column
FKS11301743250 mm4 mmAnalytical Column
FISDX05499450 mm4 mmGuard Column
Catalog number FISDX054993
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Length (Metric):
250 mm
Diameter (Metric):
4 mm
Column Format:
Analytical Column

Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants. Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

Multiple Formats for Greater Flexibility
  • ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group
  • Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semi-prep work
Superior Performance for Protein Analysis
  • Ideal for characterization and quality control assessment of MAbs and other proteins
  • Well-suited for characterization of related protein variants including deamidation and MAb lysine truncation variants
  • Unequaled high-resolution separations
  • Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.
Specifications
Column FormatAnalytical Column
Diameter (Metric)4 mm
Flow Rate1 mL/min
Length (Metric)250 mm
Max. Pressure3000 psi (207 bar)
Mobile Phase CompatibilitypH 2 to 12, 80% compatible with acetonitrile and acetone, compatible with nonionic and zwitterionic detergents, incompatible with cationic detergents
Particle Size10 μm
pH2 to 12
Pore SizeNonporous
QuantityEach
Temperature60°C
Stationary PhaseCarboxylate
Product LineProPac
Packing MaterialSpherical, Nonporous Polymer
Column TypeIon Exchange
PhaseIon Exchange
TypeAnalytical Column
TechniqueBio-LC
Green FeaturesResponsibly packaged
Unit SizeEA