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DBZ
Notch pathway inhibitor; Inhibits γ-secretase
| Catalog Number | Quantity |
|---|---|
| FIS73092 | 10 mg |
Catalog number FIS73092
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Quantity:
10 mg
- DBZ is a diazepine inhibitor of γ-secretase, which cleaves transmembrane proteins including Notch, amyloid precursor protein (APP), and Ephrin-B2 (Borgegard et al)
- DBZ blocks the cleavage of Notch into its active signalling effector, Notch intracellular domain, with an IC50 of 1.7 nM (Milano et al.)
Specifications
CAS209984-56-5
SynonymDibenzazepine, YO-01027
Quantity10 mg
Molecular FormulaC26H23F2N3O3
Purity≥98%
Unit SizeEA