DBZ
DBZ
Actual product may vary
Thermo Scientific

DBZ

Notch pathway inhibitor; Inhibits γ-secretase
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Catalog NumberQuantity
FIS7309210 mg
Catalog number FIS73092
Price (SGD)
-
Quantity:
10 mg
  • DBZ is a diazepine inhibitor of γ-secretase, which cleaves transmembrane proteins including Notch, amyloid precursor protein (APP), and Ephrin-B2 (Borgegard et al)
  • DBZ blocks the cleavage of Notch into its active signalling effector, Notch intracellular domain, with an IC50 of 1.7 nM (Milano et al.)
Specifications
CAS209984-56-5
SynonymDibenzazepine, YO-01027
Quantity10 mg
Molecular FormulaC26H23F2N3O3
Purity≥98%
Unit SizeEA