RN 1747, Tocris Bioscience™
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RN 1747, Tocris Bioscience™
RN 1747, Tocris Bioscience™
RN 1747, Tocris Bioscience™

RN 1747, Tocris Bioscience™

Selective TRPV4 agonist
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Catalog NumberQuantity
37451010 mg
Catalog number 374510
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Quantity:
10 mg
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Specifications
Chemical Name or MaterialRN 1747
CAS1024448-59-6
Recommended StorageStore at +4°C
Molecular FormulaC17H18ClN3O4S
Quantity10 mg
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Selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively). Displays selectivity over other TRP channels (EC50 values are 0.77, >30, >30 and >100 μM for TRPV4, TRPM8, TRPV3 and TRPV1 receptors respectively). Also antagonizes TRPM8 at relevant concentrations (IC50 = 4 μM).